Thursday, March 12, 2009

Lithotripsy

PROCEDURE OF THE DAY

Lithotripsy

Extracorporeal Shock Wave Lithotripsy (ESWL) is the non-invasive treatment of kidney stones (urinary calculosis) and biliary calculi (stones in the gallbladder or in the liver). Lithotripsy and the lithotriptor were developed in the early 1980s in Germany by Dornier Medizintechnik GmbH (now known as Dornier MedTech Systems GmbH), and came into widespread use with the introduction of the HM-3 lithotriptor in 1983. Within a few short years, ESWL became a standard treatment of calculosis.

It is estimated that more than one million patients are treated annually with ESWL in the USA alone.

How it works
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The lithotriptor attempts to break up the stone with minimal collateral damage by using an externally-applied, focused, high-intensity acoustic pulse. The sedated or anesthesized patient lies down in the apparatus' bed, with the back supported by a water-filled coupling device placed at the level of kidneys. A fluoroscopic x-ray imaging system or an ultrasound imaging system is used to locate the stone and aim the treatment head so that the focal point of the parabola of the shock wave is focused on the stone. The treatment usually starts at the equipment's lowest power level, with a long gap between pulses, in order to accustom the patient to the sensation. The frequency of pulses and the power level are then gradually increased, so as to break up the stone more effectively. The final power level usually depends on the patient's pain threshold. If the stone is positioned near a bone (usually a rib in the case of kidney stones), this treatment may be more uncomfortable because the shock waves can cause a mild resonance in the bone which can be felt by the patient. The sensation of the treatment is likened to an elastic band twanging off the skin. Alternately the patient may be sedated during the procedure. This allows the power levels to be brought up more quickly and a much higher pulse frequency, often up to 120 shocks per minute.

The successive shock wave pressure pulses result in direct shearing forces, as well as cavitation bubbles surrounding the stone, which fragment the stones into smaller pieces that then can easily pass through the ureters or the cystic duct. The process takes about an hour. A ureteral stent (a kind of expandable hollow tube) may be used at the discretion of the urologist. The stent allows for easier passage of the stone by relieving obstruction and through passive dilatation of the ureter.
Some of the passed fragments of a 1-cm calcium oxalate stone that was smashed using lithotripsy.

Extracorporeal lithotripsy works best with stones between 4 mm and 2 cm in diameter that are still located in the kidney. It can be used to break up stones which are located in a ureter too, but with less success.

The patients undergoing this procedure can, in some cases, see for themselves the progress of their treatment. If allowed to view the ultrasound or x-ray monitor, they may be able to see their stones change from a distinct bright point (or dark spot depending on whether the fluoro unit is set up in native or bones white) to a fuzzy cloud as the stone is disintegrated into a fine powder.

ESWL is the least invasive of the commonplace modalities for definitive stone treatment, but provides a lower stone-free rate than other more invasive treatment methods, such as ureteroscopic manipulation with laser lithotripsy or percutaneous nephrolithotomy (PCNL). The passage of stone fragments may take a few days or a week and may cause mild pain. Patients may be instructed to drink as much water as practical during this time. Patients are also advised to void through a stonescreen in order to capture stone fragments for analysis.

A patient of the procedure has equated the after effects to "a punch to the kidney" (pain while urinating, sometimes with blood).

ESWL is not without risks. The shock waves themselves, as well as cavitation bubbles formed by the agitation of the urine medium, can lead to capillary damage, renal parenchymal or subcapsular hemorrhage. This can lead to long-term consequences such as renal failure and hypertension. Overall complication rates of ESWL range from 5–20%.

Shock waves can be deadly.


FRAGMENTS OF A 1 CM KIDNEY STONE

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